Andreas Junker, MD

 

Publications

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Original papers

1. Michel A, Darkwah Oppong M, Rauschenbach L, Dinger TF, Barthel L, Pierscianek D, Wrede KH, Hense J, Pöttgen C, Junker A, Schmidt T, Iannaccone A, Kimmig R, Sure U, Jabbarli R. Prediction of Short and Long Survival after Surgery for Breast Cancer Brain Metastases. Cancers (Basel). 2022 Mar 10;14(6):1437. (6,162)

 

2. Sato T, Matsushige T, Chen B, Gembruch O, Dammann P, Jabbarli R, Forsting M, Junker A, Maderwald S, Quick HH, Ladd ME, Sure U, Wrede KH. Correlation Between Thrombus Signal Intensity and Aneurysm Wall Thickness in Partially Thrombosed Intracranial Aneurysms Using 7T Magnetization-Prepared Rapid Acquisition Gradient Echo Magnetic Resonance Imaging. Front Neurol. 2022 Feb 18;13:758126. (3,62)

 

3. Michel A, Oppong MD, Rauschenbach L, Pierscianek D, Dinger TF, Schmidt T, Hense J, Pöttgen C, Kimmig R, Ahmadipour Y, Özkan N, Müller O, Junker A, Sure U, Jabbarli R, El Hindy N. HER2 Receptor Conversion Is a strong Survival Predictor in Patients with Breast Cancer Brain Metastases. World Neurosurg. 2021 Aug;152:e332-e343. (2,104)

 

4. Teuber-Hanselmann S, Worm K, Macha N, Junker A. MGMT-Methylation in Non-Neoplastic Diseases of the Central Nervous System. Int J Mol Sci. 2021 Apr 8;22(8):3845 (5,924)

 

5. Ahmadipour Y, Rauschenbach L, Santos A, Darkwah Oppong M, Lazaridis L, Quesada CM, Junker A, Pierscianek D, Dammann P, Wrede KH, Scheffler B, Glas M, Stuschke M, Sure U, Jabbarli R. Preoperative and early postoperative seizures in patients with glioblastoma-two sides of the same coin? Neurooncol Adv. 2020 Nov 18;3(1):vdaa158 (10,091)

 

6. Rodemerk J, Junker A, Chen B, Pierscianek D, Dammann P, Darkwah Oppong M, Radbruch A, Forsting M, Maderwald S, Quick HH, Zhu Y, Jabbarli R, Sure U, Wrede KH. Pathophysiology of Intracranial Aneurysms: COX-2 Expression, Iron Deposition in Aneurysm Wall, and Correlation With Magnetic Resonance Imaging. Stroke. 2020 Aug;51(8):2505-2513. (6,928)

 

7. Jäckle K, Zeis T, Schaeren-Wiemers N, Junker A, van der Meer F, Kramann N, Stadelmann C, Brück W. Molecular signature of slowly expanding lesions in progressive multiple sclerosis. Brain. 2020 Jul 1;143(7):2073-2088. (10,75)

 

8. Junker A*, Wozniak J*, Voigt D, Scheidt U, Antel J, Wegner C, Brück W, Stadelmann C. Extensive subpial cortical demyelination is specific to multiple sclerosis. Brain Pathol. 2020 May;30(3):641-652. (4,859)

 

9. Fritsche L, Teuber-Hanselmann S, Soub D, Harnisch K, Mairinger F, Junker A. MicroRNA profiles of MS gray matter lesions identify modulators of the synaptic protein synaptotagmin-7. Brain Pathol. 2020 May;30(3):524-540. (4,859)

 

10. Goebel J, Gaida BJ, Wanke I, Kleinschnitz C, Koehrmann M, Forsting M, Moenninghoff C, Radbruch A, Junker A. Is Histologic Thrombus Composition in Acute Stroke Linked to Stroke Etiology or to Interventional Parameters? AJNR Am J Neuroradiol. 2020 Apr;41(4):650-657. (3,515)

 

11. Sato T, Matsushige T, Chen B, Gembruch O, Dammann P, Jabbarli R, Forsting M, Junker A, Maderwald S, Quick HH, Ladd ME, Sure U, Wrede KH. Wall Contrast Enhancement of Thrombosed Intracranial Aneurysms at 7T MRI. AJNR Am J Neuroradiol. 2019 Jul;40(7):1106-1111. (3,515)

 

12. Harnisch K, Teuber-Hanselmann S, Macha N, Mairinger F, Fritsche L, Soub D, Meinl E, Junker A. Myelination in Multiple Sclerosis Lesions Is Associated with Regulation of Bone Morphogenetic Protein 4 and Its Antagonist Noggin. Int J Mol Sci. 2019 Jan 3;20(1):154. (4,207)

 

13. Schultz V, van der Meer F, Wrzos C, Scheidt U, Bahn E, Stadelmann C, Brück W*, Junker A*. Acutely damaged axons are remyelinated in multiple sclerosis and experimental models of demyelination. Glia. 2017 Aug;65(8):1350-1360. (5,944)

 

14. Voigt D, Scheidt U, Derfuss T, Brück W, Junker A. Expression of the Antioxidative Enzyme Peroxiredoxin 2 in Multiple Sclerosis Lesions in Relation to Inflammation. Int J Mol Sci. 2017 Apr 4;18(4):760. (3,925)

 

15. Gerdes LA, Held K, Beltrán E, Berking C, Prinz JC, Junker A, Tietze JK, Ertl-Wagner B, Straube A, Kümpfel T, Dornmair K, Hohlfeld R. CTLA4 as Immunological Checkpoint in the Development of Multiple Sclerosis. Ann Neurol. 2016 Aug;80(2):294-300. (10,419)

 

16. Mohan H, Friese A, Albrecht S, Krumbholz M, Elliott CL, Arthur A, Menon R, Farina C, Junker A, Stadelmann C, Barnett SC, Huitinga I, Wekerle H, Hohlfeld R, Lassmann H, Kuhlmann T, Linington C, Meinl E. Transcript profiling of different types of multiple sclerosis lesions yields FGF1 as a promoter of remyelination. Acta Neuropathol Commun. 2014 Dec 11;2:168. (5,414)

 

17. Lescher J, Paap F, Schultz V, Redenbach L, Scheidt U, Rosewich H, Nessler S, Fuchs E, Gärtner J, Brück W, Junker A. MicroRNA regulation in experimental autoimmune encephalomyelitis in mice and marmosets resembles regulation in human multiple sclerosis lesions. J Neuroimmunol. 2012 May 15;246(1-2):27-33 (3,583)

 

18. Eisele S, Krumbholz M, Fischer MT, Mohan H, Junker A, Arzberger T, Hohlfeld R, Bradl M, Lassmann H, Meinl E. Prospects of Transcript Profiling for mRNAs and MicroRNAs Using Formalin-Fixed and Paraffin-Embedded Dissected Autoptic Multiple Sclerosis Lesions. Brain Pathol 2012 Sep;22(5):607-18. (5,489)

 

19. Held K, Junker A, Dornmair K, Meinl E, Sinicina I, Brandt T, Theil D, Derfuss T. Expression of HSV-1 encoded miRNAs in human trigeminal ganglia and their relation to local T-cell infiltrates. J Virol. 2011 Oct;85(19):9680-5. (5,15)

 

20. Mohan H, Krumbholz M, Sharma R, Eisele S, Junker A, Sixt M, Newcombe J, Wekerle H, Hohlfeld R, Lassmann H, Meinl E. Extracellular matrix in multiple sclerosis lesions: Fibrillar collagens, biglycan and decorin are upregulated and associated with infiltrating immune cells. Brain Pathol. 2010 Sep;20(5):966-75. (4,429)

 

21. Junker A, Krumbholz M, Eisele S, Mohan H, Augstein F, Bittner R, Lassmann H, Wekerle H, Hohlfeld R, Meinl E. MicroRNA profiling of multiple sclerosis lesions identifies modulators of the regulatory protein CD47. Brain. 2009 Dec;132(Pt 12):3342-52. (10,099)

 

22. Junker A*, Ivanidze J*, Malotka J, Eiglmeier I, Lassmann H, Wekerle H, Meinl E, Hohlfeld R, Dornmair K. Multiple sclerosis: T-cell receptor expression in distinct brain regions. Brain. 2007 Nov;130(Pt 11):2789-99. (9,022)

 

23. Krumbholz M, Theil D, Steinmeyer F, Cepok S, Hemmer B, Hofbauer M, Farina C, Derfuss T, Junker A, Arzberger T, Sinicina I, Hartle C, Newcombe J, Hohlfeld R, Meinl E. CCL19 is constitutively expressed in the CNS, up-regulated in neuroinflammation, active and also inactive multiple sclerosis lesions. J Neuroimmunol. 2007 Oct;190(1-2):72-79. (3,247)

 

24. Brettschneider J, Petzold A, Junker A, Tumani H. Axonal damage markers in the cerebrospinal fluid of patients with clinically isolated syndrome improve predicting conversion to definite multiple sclerosis. Multiple sclerosis 2006; 12: 143-148. (3,387)

 

* Publications with shared first or last authorship.

 

Case reports:

 

25. Escolà JK, Deuschl C, Junker A, Dusse F, Pul R, Kleinschnitz C, Köhrmann M, Frank B. MOG antibody-associated encephalomyelitis mimicking bacterial meningomyelitis following ChAdOx1 nCoV-19 vaccination: a case report. Ther Adv Neurol Disord. 2022 Jan 19;15:17562864211070684 (5,111)

 

26. Loesch-Biffar AM, Junker A, Linn J, Thon N, Heck S, Ottomeyer C, Straube A, Pfister HW. Minimal Neurological Deficit of Two Adult Patients With Weston-Hurst Syndrome Due to Early Craniectomy: Case Series and Review of Literature on Craniectomy. Front Neurol 2021 Aug 31;12:673611. (4,003)

 

27. Schmidt T, Kebir S, Livingstone E, Junker A, Zülow S, Lazaridis L, Oster C, Chorti E, Pierscianek D, Pul R, Keyvani K, Sure U, Stuschke M, Kleinschnitz C, Scheffler B, Zimmer L, Glas M. Pseudomeningeosis and Demyelinating Metastasis-Like Lesions From Checkpoint Inhibitor Therapy in Malignant Melanoma. Front Oncol. 2021 Apr 15;11:637185. (5,66)

 

28. Stoppek AK, Kebir S, Junker A, Keyvani K, Zülow S, Lazaridis L, Schmidt T, Pierscianek D, Stuschke M, Sure U, Kleinschnitz C, Scheffler B, Zimmer L, Glas M. Simultaneous primary cancer occurrence of melanoma and pulmonary adenocarcinoma in leptomeningeal metastases: a case report. BMC Cancer. 2019 Oct 23;19(1):995. (3,211)

 

29. Stettner M, Gross CC, Mausberg AK, Pul R, Junker A, Baba HA, Schulte-Mecklenbeck A, Wiendl H, Kleinschnitz C, Meuth SG. A fatal case of daclizumab-induced liver failure in a patient with MS. Neurol Neuroimmunol Neuroinflamm. 2019 Jan 21;6(2):e539. (7,724)

 

30. Gembruch O, Junker A, Ahmadipour Y, Sure U, Lemonas E. Cerebellar liponeurocytoma - a rare entity: a case report. J Med Case Rep. 2018 Jun 17;12(1):170. (0,659)

 

31. Krogias C, Gold R, Schelle T, Böhm J, Junker A, Sure U, Uerschels AK. Teaching NeuroImages: Sonographic detection of intraneural perineurioma in therapy-refractory carpal tunnel syndrome. Neurology. 2017 Mar 7;88(10):e85-e86. (6,939)

 

 

Review article

 

32. Jabbarli R, Rauschenbach L, Dinger TF, Darkwah Oppong M, Rodemerk J, Pierscianek D, Dammann P, Junker A, Sure U, Wrede KH. In the wall lies the truth: a systematic review of diagnostic markers in intracranial aneurysms. Brain Pathol. 2020 May;30(3):437-445. (4,859)

 

33. Teuber-Hanselmann S, Meinl E, Junker A. MicroRNAs in gray and white matter multiple sclerosis lesions: impact on pathophysiology. J Pathol. 2020 Apr;250(5):496-509. (6,031)

 

34. Uerschels AK, Krogias C, Junker A, Sure U, Wrede KH, Gembruch O. Modern treatment of perineuriomas: a case-series and systematic review. BMC Neurol. 2020 Feb 13;20(1):55. (2,475)

 

35. Gembruch O, Junker A, Mönninghoff C, Ahmadipour Y, Darkwah Oppong M, Sure U, El Hindy N, Lemonas E. Liponeurocytoma: Systematic Review of a Rare Entity. World Neurosurg. 2018 Dec;120:214-33. (1,65)

 

36. Abdelhak A, Junker A, Brettschneider J, Kassubek J, Ludolph AC, Otto M, Tumani H. Brain-Specific Cytoskeletal Damage Markers in Cerebrospinal Fluid: Is There a Common Pattern between Amyotrophic Lateral Sclerosis and Primary Progressive Multiple Sclerosis? Int J Mol Sci. 2015 Jul 31;16(8):17565-88. (3,257)

 

37. Junker A, Brück W. Autoinflammatory grey matter lesions in humans: cortical encephalitis, clinical disorders, experimental models. Curr Opin Neurol. 2012 Jun;25(3):349-57 (6,071)

 

38. Junker A. Pathophysiology of translational regulation by microRNAs in multiple sclerosis. FEBS Lett. 2011 Dec 1;585(23):3738-46. (2,302)

 

39. Junker A, Meinl E, Hohlfeld R. Nature Reviews Neurology, Emerging role of miRNAs in multiple sclerosis. Nat Rev Neurol. 2011 Jan;7(1):56-59. (4,682)

 

40. Meinl E, Krumbholz M, Derfuss T, Junker A, Hohlfeld R. Compartmentalization of inflammation in the CNS: a major mechanism driving progressive multiple sclerosis. J Neurol Sci. 2008 Nov 15;274(1- 2):42-44. (2,583)

 

Book contributions

 

41. Junker A. MicroRNA regulation in multiple sclerosis. MicroRNAs in Medicine. Edited by Charles H. Lawrie. John Wiley & Sons; 1. Edition (27. Dec. 2013)